Description
Urilef Tablets 100mg 30 Tablets Specification
Requires Prescription (YES/NO)
Yes
Generics
Phenazopyridine HCl
Used For
Urinary Tract Infection
How it works
Phenazopyridine HCl is excreted in the urine where it exerts a topical analgesic effect on the mucosa of the urinary tract. This action helps to relieve pain, burning, urgency and frequency. The precise mechanism of action is unknown.
Usage And Safety
Dosage
Recommended Dose and Dosage Adjustment Adults: 200mg 3 times daily after meals. Children: 12mg/kg/day in 3 divided doses for 2 days. When used concomitantly with an antibacterial agent for the treatment of a urinary tract infection, the administration of Phenazopyridine HCl should not exceed 2 days. If symptoms persist, the patient should be re-evaluated. Always ask your physician or pharmacist for dose adjustments.
Side Effects
Nausea, vomiting, diarrhea, headache, aseptic meningitis, rash, pruritus, discoloration, jaundice, renal toxicity usually associated with overdose, renal calculi, methemoglobinemia, hemolytic anemia, acute renal failure, potential hemolytic agent in G-6-PD deficiency, sulfhemoglobinemia, anaphylactoid-like reaction, hypersensitivity, hepatitis, visual disturbances, eye irritation, ear pain, reversible loss of colour vision, hepatic toxicity usually associated with overdose, discoloration of body fluids, crystal deposits of phenazopyridine have formed in the urinary tract and aseptic meningitis, with distinct episodes of fever and confusion .
Drug Interactions
Ciprofloxacin
Indication
Phenazopyridine HCl is indicated for the symptomatic relief of pain and irritability in conditions such as cystitis, prostatitis and urethritis; burning, urgency, frequency and other discomforts resulting from irritation of the mucosa of the lower urinary tract caused by infection, trauma, surgery, endoscopic procedures or the passage of sounds or catheters.
When not to Use
Phenazopyridine HCl is contraindicated; • In patients with known hypersensitivity to Phenazopyridine HCl or to any excipient of the product. • In patients with renal insufficiency (including glomerulonephritis, uremia, pyelonephritis during pregnancy or impaired renal function). • In patients with severe liver disease.
Precautions
Precaution
Phenazopyridine HCl produces an orange to red colour in the urine and feces and may cause staining. Phenazopyridine HCl may cause discoloration of body fluids and staining of contact lenses has been reported. A yellowish colour of the skin or sclerae may indicate accumulation of Phenazopyridine HCl resulting from impaired renal function and necessitates discontinuance of the drug. It should be noted that a decline in renal function is common in elderly patients.
Warnings
Warning 1
Cautious use in patients with G-6-PD deficiency is advised since these patients are susceptible to oxidative hemolysis and may have greater potential to develop hemolytic anemia .
Warning 2
The use of Phenazopyridine HCl for relief of symptoms should not delay definitive diagnosis and treatment of causative conditions. The drug should be used for symptomatic relief of pain and not as a substitute for specific surgery or antimicrobial therapy .
Warning 3
Avoid prolong use in pregnancy and lactation, stop treatment if skin or sclerae discoloration occur.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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